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These phagocytes can act as endothelial activators through the release of extracellular neutrophil traps (NETs)
Disruption of blood-brain barrier integrity in postmortem alcoholic brain: Preclinical evidence of TLR4 involvement from a binge-like drinking model
However, gastrointestinal side effectsparticularly nauseacan be pronounced, especially during dose escalation
The overall summary is provided in this Cochrane review (Strippoli et al, CDSR, 2006)
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