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Semaglutide 2.4 mg, the active ingredient in Wegovy, produced a mean body weight reduction of 14.9% versus 2.4% with placebo over 68 weeks in the STEP-1 trial (N=1,961) [1]
Methods A systematic search was conducted in five databases using established keywords
Moreover, the success of semaglutide in weight management has led to its approval for use specifically in the treatment of obesity, underlining its role as a cornerstone therapy
About half of the drug is removed in roughly five to six days, while the remaining amount continues declining through several additional half-life cycles
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