The position of the supraorbital and supratrochlear neurovascular bundles, the depth of the SMAS layer over the malar fat pad, the convexity of the zygomatic body, the trajectory of the facial artery as it crosses the mandible, the relationship of the modiolus to the oral commissure, the thickness of the platysma and its decussation pattern across the midline neck, the variant anatomy of the angular and dorsal nasal arteries near the nasal radix: all of these change the safe injection plane, the appropriate cannula or needle, the volume that can be safely deposited, and the technique angle
However, patient experience is mixed: while some members report no difference between the two methods, others find they do not achieve the same symptom resolution with SC injections
Clinical studies show that B12 injections have no major side effects, though rare cases of sensitivity may occur [20]
Sun H, Yang B, Li Q, et al (2024) Polystyrene nanoparticles trigger aberrant condensation of TDP-43 and amyotrophic lateral sclerosis-like symptoms
(It is not as scary or as challenging as it may seem at first)