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doi: 10.1093/jn/132.5.1012 270
Maximum Bioavailability: The film format bypasses the liver's "first-pass effect," allowing the liposomal glutathione to be absorbed directly through the thin tissues of the mouth
Additionally, other NRF2-regulated enzymatic processes, such as quinone detoxification by NQO1 and aldo-keto reductase (AKR), also require NADPH
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These strategies are useful for a variety of biomedical applications, including drug delivery, imaging, sensing, and theranostics as they can "switch-on" certain functions upon exposure to such intrinsic incitements, such as cargo release from a carrier, enhanced fluorescence output, and higher affinity towards specific biomolecules 4
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