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It does not contain caffeine, and it is produced naturally by the liver and kidney as well as stored primary in the skeletal muscle (98%)

By replacing NAFLD with MAFLD, several aspects of this disease were changed, including terminology, details of the definition, pathogenesis, associated disease, and, crucially, the aspects of research and drug development demonstrated in Table 1

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It is important to distinguish between theoretical concerns based on mechanism of action and actual clinical evidence of harm

GLP-1 receptor agonists slow gastric emptying and reduce appetite, which can lead to constipation and other gastrointestinal symptoms