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Cheong MJ, Kim S, Kim JS, et al

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Symptoms include sharp, stabbing pain in the heel and tenderness in the bottom of the foot that worsens with walking or prolonged periods of standing

While the molecule comes from a different biological source and its DNA fragment profile may differ from traditional salmon-derived PDRN, she notes that "based on available research, plant PDRN appears to work through the same A2A receptor mechanism as salmon-derived PDRN." In other words, it appears to activate the same pathways involved in skin repair, wound healing, inflammation regulation, and collagen production, meaning it may deliver many of the same skin-repairing and regenerative benefits despite coming from an entirely different source

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