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When your body builds type I collagen (the dominant structural protein in tendons, ligaments, skin, and bone), it clips off P1NP as a byproduct
Otto, M
Metabolic Safety: IGF-1 and Glucose Effects One of the most clinically significant safety findings relates to AOD-9604s metabolic profile, particularly its lack of effects on insulin-like growth factor-1 (IGF-1) and glucose metabolism
A meta-analysis of 35 randomized controlled trials (3,165 patients) found that collagen supplementation significantly improved pain and function in osteoarthritis, with 56-57% reductions in pain scores and inflammatory markers
Jacobs, P
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