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Furthermore, an increased plasma von Willebrand factor is found in hyperhomocysteinemic subjects bearing premature arterial disease (Freyburger et al, 1997) and, of major relevance, acute methionine loading induced moderate hyperhomocysteinemia results in a significant increase in von Willebrand factor (Constant et al, 1999)
and (3) patients with kidney disease or on dialysis should consult their physician, as carnitine clearance drops significantly in renal impairment
Our findings supported their findings regarding HbA1c reduction and the time spent in hyperglycemia
For this reason, ongoing monitoring is important
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