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( / mice liver experienced senescence characterized by cell cycle arrest, which favored the proliferation of donor hepatocytes ( The Hippo pathway, critical for liver regeneration, comprised of MST1/2 phosphorylating and activating the LATS1/2, which then phosphorylates and inactivates YAP and TAZ

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The doxorubicin cardiotoxicity studies are particularly noteworthy because this chemotherapy drug causes a type of heart damage that closely resembles natural cardiomyopathy

PMID: 15455129