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The central marker is IGF-1, which reflects growth hormone activity

Zepbound (tirzepatide) is prescribed for adults with a Body Mass Index (BMI) of 30 or higher (obesity), or a BMI of 27 or higher (overweight) who also have at least one weight-related comorbidity such as type 2 diabetes, high blood pressure, or high cholesterol

Retatrutide is administered as a subcutaneous injection, typically once weekly

However, any unusual symptoms should be reported to a healthcare provider

The 2023 International Evidence-Based Guideline for PCOS, published before the PMOS name change, stated that anti-obesity medications, including GLP-1 receptor agonists such as liraglutide and semaglutide, could be considered in addition to lifestyle intervention for adults with PCOS and higher weight