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57,59 Exenatide, a synthetic peptide with 50% sequence homology to GLP-1, is resistant to dipeptidyl peptidase-4-mediated degradation 54 and was the first GLP-1RAs approved by the US Food and Drug Administration (FDA) for T2DM treatment in 2005

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Some people use the standard 0.25 mg dose but inject every 10 to 14 days instead of every 7

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found that genes related to oxidative stress were down-regulated such as SOD1 and SOD2 (28), and Mindikoglu et al