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GLP-1-class drugs amplify this in one indirect way: they work largely by suppressing appetite, which can drive protein intake and overall calories very low if a person simply "isn't hungry." Under-eating protein while losing weight quickly is the single biggest driver of avoidable muscle loss
Eight healthy volunteers also made a one-time donation of their blood for preclinical studies to establish a baseline against the clinical trial T2DM subjects
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Galland, F
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