Los estudios clnicos (Leyden 2002) reportan mejoras significativas a las 12 semanas con aplicacin 2 veces/da
Nunes J, Andrieux P, Brochet P, Almeida RR, Kitano E, Honda AK, Iwai LK, Andrade-Silva D, Goudenge D, Alcntara Silva KD, Vieira RS, Levy D, Bydlowski SP, Gallardo F, Torres M, Bocchi EA, Mano M, Santos R, Bacal F, Pomerantzeff P, Laurindo F, Teixeira PC, Nakaya HI, Kalil J, Procaccio V, Chevillard C, Cunha-Neto E
The effects are not as good as oral supplementation, & we do not routinely add this to your melasma or skin lightening program
After washing off excess dye, biopsies can be obtained from segments that stain intensely blue to improve the diagnostic yield
Those who smoke, as theyre exposed to more cyanide