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Therefore, it is important to distinguish between diseases in which oxidative damage plays a primary causal role and those in which it represents a late-stage consequence
Several of those together warrant a GP visit
(A) Senolytic agents selectively induce the apoptosis of senescent cells by inhibiting the pro-survival signaling pathways, including PI3K/Akt, BCL-2 family proteins, p53/MDM2, and HSP90
Data availability The datasets used and analysed during the current study are available from the corresponding author on reasonable request
found that TMAO induced mitochondrial dysfunction, thereby decreasing contractility of cardiomyocytes (100)
