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(5.2) Hypoglycemia with Concomitant Use of Insulin Secretagogues or Insulin: Concomitant use with an insulin secretagogue or insulin may increase the risk of hypoglycemia, including severe hypoglycemia

Injecting semaglutide into muscle (intramuscular) rather than subcutaneous tissue can affect absorption rates and may increase pain or bruising

Standardised guidelines for patient education and clinical support with GLP-1 RAs may help improve quality and consistency of care, leading to better expectation management around likely adverse effects, mitigation strategies, and long-term management, the authors concluded

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