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TB001 treatment also reduced the body weight of recipients ( P = 0.0002, Figure 1E ) without affecting the weight of the transplanted kidneys, as evidenced by a higher graft-to-body weight ratio in the TB001 group ( P = 0.037, Figure 1F )
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Exposure to SGLT2 inhibitors from postnatal day 21 to 90, the period functionally coinciding with the late second and third trimesters of human pregnancy regarding kidney development, caused dilatation of the renal pelvis and tubules ( Table 2 )
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