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One large observational study of 461,382 patients taking GLP-1 medications found that 15.1% developed vitamin deficiencies over 12 months, including 13.6% with vitamin D deficiency, 0.0% with niacin deficiency, and 0.1% with thiamine deficiency
Next, to assess whether this early motor deficit was also rescued by the downregulation of Gsto2 , additional cohorts of mutants were injected at 3 months with Gsto2 -shRNA or scrambled shRNA and tested 3 weeks later for unsupported rearing
Ozkul A, Akyol A, Yenisey C, et al
2008;135:205564 (2064.e1-2)
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