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Symptoms of a severe allergic reaction include difficulty breathing, swelling of the face or throat, rapid heartbeat, hives, and a sudden drop in blood pressure
Mechanistically, alterations in gut microbial metabolites such as SCFAs could affect the integrity of the BBB, induce systemic endotoxemia, and activate microglia so as to impact disease progression
"Depletion of phospholipid hydroperoxide glutathione peroxidase up-regulates arachidonate metabolism by 12S-lipoxygenase and cyclooxygenase 1 in human epidermoid carcinoma A431 cells"
Brain-derived neurotrophic factor (BDNF) mRNA in rats with neonatal ibotenic acid lesions of the ventral hippocampus
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