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18 A hallmark of MDR is the dysregulation of intracellular drug availability, primarily through impaired drug uptake and enhanced drug efflux, involving the SLC and ABC transporter families

In addition to NPY this family is composed of two gut hormones, pancreatic polypeptide (PP) and peptide tyrosine-tyrosine (PYY) both of which are discussed below

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The blend sits a step below both: its case is a mechanistic argument built by combining those two literatures, and it has not been tested as a product

(2026, January 8)