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Compounded semaglutide contains the same active ingredient but is prepared by licensed 503B compounding pharmacies under FDA oversight
Animal models show prolonged use can drive organ hypertrophy (heart, intestines)
As a result, it promotes CREB1 transcription and M2 macrophage polarization
It sits between tirzepatide (around 14.9% in SURMOUNT-1) and semaglutide (around 6.9% in STEP-1)
Heart palpitations can be super unsettling, especially when anxiety is the one pulling the strings
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