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[7] In parallel, Merck developed MK-677 (ibutamoren), a non-peptide oral GH secretagogue acting through the same receptor, demonstrating that small molecules could also activate this pathway
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Behavioral tests, including the rotarod test, assessed the motor coordination and neuromuscular function, and revealed significant improvements in the Curcumin-PLGA nanoparticles + LIFU group, compared to those treated with Curcumin-PLGA nanoparticles alone, LIFU alone, or untreated PD model mice
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