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A systematic review with meta-analysis on 33 data sets with at least 10 years follow up, including a single center with 20 years of follow-up, found significant and sustained weight loss after surgery

Here, we determine structures of cagrilintide bound to Gs-coupled, active, amylin receptors (AMY 1 R, AMY 2 R, AMY 3 R) and calcitonin receptor (CTR) and compare cagrilintide interactions and the dynamics of receptor complexes with previously reported structures of receptors bound to rat amylin, salmon calcitonin or recently developed amylin-based peptides