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Researchers study MOTS-C for insulin resistance, obesity, exercise performance, and aging - particularly for its role in metabolic regulation and longevity signaling

A peptide might cause one or a handful of intracellular events, while a steroid hormone can flip on sweeping gene programs and ripple across tissues

AD has two hallmark pathologies: extracellular beta-amyloid plaques [217] and neurofibrillary tangles composed of hyperphosphorylated tau [218]

Unlike benzodiazepines or other sedatives, it doesn't appear to create tolerance requiring escalating doses or produce withdrawal symptoms upon cessation

Rosenstock et al