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The NOS1 gene is located on chromosome 12q24.22 and is composed of 33 exons the generate four alternatively spliced mRNAs that collectively encode three distinct protein isoforms
Neuronal NOS is also expressed within smooth muscle cells of the penile corpus cavernosum and thus, NO produced by this enzyme is involved in penile erection
Being the most abundant antioxidant inside the cells, GSH can directly scavenge free radicals (OH , O 2 - and organic free radicals) (Yu, 1994) or act as a cosubstrate in the GSH-Px-catalyzed reduction of H 2 O 2 and lipid hydroperoxides, a constituent of cell membranes (Loughrey et al., 1994
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