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Phase 1b/2a Subcutaneous Formulation (Obesity) Published: The Lancet, June 2025 Participants: 125 adults with overweight or obesity (BMI 27.039.9), aged 1855 Duration: Up to 36 weeks Dosing: Once-weekly subcutaneous amycretin, up to 60 mg Results: - Up to 22% absolute weight loss at 36 weeks (highest dose group) - Placebo-adjusted difference: approximately 24% - No weight-loss plateau observed at study end Safety: 81% of the 89 participants who reported a TEAE had gastrointestinal events
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Similar content being viewed by others Introduction Oxidative stress has been suggested as a possible etiology in a number of neurodegenerative diseases, including Alzheimers disease (AD), Parkinson's disease (PD) and amyotrophic lateral sclerosis (ALS) 1
This is the key advantage of IV delivery over oral supplements: your gut significantly breaks down oral glutathione before it reaches systemic circulation
