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Methods Cell lines and human samples Human Burkitt lymphoma DG-75 (CRL-2625) and BL-2 (ACC-625), T-cell leukemia Jurkat (Clone E6-1, TIB-152), and HEK-293T (CRL-1573) cell lines were obtained from ATCC (LGC Standards S.L.U., Barcelona, Spain)

Severe or refractory RLS symptoms may warrant referral to a sleep medicine specialist or neurologist

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As such, patients and healthcare providers must work closely to navigate these challenges and ensure that patients can access the medications they need