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Treatment with Dihexa at doses of 1.44-2.88 mg/kg administered intragastrically for three months significantly reduced escape latency and increased time spent in the target quadrant during probe trials
When copper handling is impaired, reactive copper may increase oxidative stress and place greater demand on glutathione and other antioxidant defenses
It is crucial to note, however, that recent studies highlight significant systemic side effects of MCT4 inhibition due to its broad tissue expression, which may limit its clinical translational potential and necessitate the development of tissue-specific delivery strategies [138]
Beneficial Effects of N-acetylcysteine and N-mercaptopropionylglycine on Ischemia Reperfusion Injury in the Heart
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