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Interestingly, a tight bi-directional interaction of L cells and enterochromaffin cells has been described, with L cells expressing serotonin receptor 4 (51) and enterochromaffin cells expressing GLP-1 receptor (52)
Glucagon directly increases energy expenditure by promoting the breakdown of stored glycogen and enhancing thermogenesis
Many patients find linking this routine to an existing morning habit, waking up, taking the tablet, then showering or getting ready before breakfast, makes the 30-minute wait easy to manage in practice
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