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In a cervical cancer cell line (HeLa), the compound reduced cell proliferation in a concentration- and time-dependent way and lowered expression of phospho-Akt and SIRT1, two proteins tied to tumor progression, while a non-cancer reference cell line was less affected

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This finding suggests that the NNMT-inhibiting compound has effects on pathways different from exercise training on its own and that taking it does not work the same way as exercising regularly

Follow-up Repeat broad markers after 6-12 weeks if systemic use continues or symptoms change

Fast acting but short-lived