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Researchers noted that people receiving the medication experienced statistically significant and clinically meaningful weight loss starting at 28 weeks

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Moeni I, Koli I, Nievi JR, Belani A, Tratnik JS, Mazej D, Falnoga I, Vlai-Cicvari I, timac T, piri Z, Horvat M, Prpi I

PMC A 2025 study in high-fat-dietinduced obese C57BL/6J mice found that targeted forskolin delivery to subcutaneous white fat improved several obesity-related and metabolic markers, but the authors note that more research is needed and its unclear how these findings translate to humans

Similarly, a meta-analysis by McCarty TR et al