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Cell surface integrin receptors on OLs such as 1 integrin interact with ECM ligands on axons to amplify growth factor signaling, regulating the survival of pre-myelinating and myelinating OLs, increasing myelin membrane formation, influencing axonal selection for myelination in an diameter-dependent manner, and regulating myelin gene translation 155,156,157,158,159,160
Blood testing is sometimes conducted but less common
Presented for research literature review only Gao L et al
Clinical symptoms are not always apparent
Label your vial with the reconstitution date and concentration, then store immediately in the refrigerator
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