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Many of these products, however, are laced with mercury
No dose adjustment is needed based on kidney function
Discontinuation rates range from 37% to 81% within the first year, driven by cost, side effects, and access barriers, with weight regain thereafter mediated through hormonal dysregulation, CNS maladaptation to reduced GLP-1 signaling, and -cell dysfunction
Patients tend to regain weight following cessation of elite behavior, this is why long-lasting management strategies are brought up during medical visits
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