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It separately flags hypoglycemia risk if both agents lower blood glucose meaningfully, and says that risk is higher in people already taking insulin or other glucose-lowering medications

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Individualized risk assessment, patient education, and careful dose titration are essential for optimizing long-term tolerability

The reason that they have gained so much traction so rapidly is because when we talk about why people eat, it actually turns out that the reason that people end up eating is for a few different reasons