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The dramatic results from the TRIUMPH-1 trial represent the greatest weight loss observed in a medication trial, rivaling current GLP-1 drugs and bariatric surgery

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Bernheim SM, Spertus JA, Reid KJ, Bradley EH, Desai RA, Peterson ED, Rathore SS, Normand SL, Jones PG, Rahimi A, Krumholz HM

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Less commonly advertised are the side effects of these drugs, including nausea, vomiting, diarrhea, and constipation, and more serious risks like pancreatitis, thyroid tumors, and allergic reactions

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