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Even if caloric intake remains similar, the metabolic effects can drive additional fat loss compared to GLP-1 only approaches
Semaglutide versus dulaglutide once weekly in patients with Type 2 diabetes (SUSTAIN 7): A randomised, open-label, phase 3b trial, The Lancet Diabetes & Endocrinology (2018) Ozempic semaglutide injection, solution, DailyMed (2024) Trulicity dulaglutide injection, solution, DailyMed (2024) Clinical recommendations to manage gastrointestinal adverse events in patients treated with Glp-1 receptor agonists: a multidisciplinary expert consensus, Journal of Clinical Medicine (2022) Possible side effects of Ozempic (semaglutide) injection, Novo Nordisk An indirect treatment comparison of the efficacy of semaglutide 1.0 mg versus dulaglutide 3.0 and 4.5 mg, Diabetes, Obesity and Metabolism (2021) SUSTAIN 7: Ozempic versus Trulicity, NovoMedlink Medically accurate: SingleCares Medical Review Board analyzes all of our content to confirm its in line with current medical advice
While GLP-1 therapies such as Ozempic, Wegovy, Mounjaro and Zepbound are already well established in the Canadian market, the report notes that the 2026 pipeline reflects a focus on improved efficacy, more uses and longer dosing intervals
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