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When two agonists bind the same receptor, the second one isn't adding a new signal it is competing for finite binding sites on a pathway that is already being stimulated
Melanotan-2: Broad Activation MT-2 activates all five melanocortin receptor subtypes : MC1R Melanin production (tanning) MC3R Energy homeostasis, sexual arousal MC4R Appetite regulation, sexual function, erectile response MC5R Sebaceous gland function This non-selective binding is why MT-2 produces tanning AND sexual effects AND appetite suppression AND nausea it's hitting every melanocortin pathway at once
These symptoms may indicate anaphylaxis, a medical emergency requiring prompt treatment with epinephrine
Obesity causes body-wide inflammation, which goes hand in hand with psoriasis, and this link allows GLP-1s to treat both conditions
Electrospray of a coordination complex is unreliable in a way that catches people out: the complex can dissociate in the source, so the ion you observe may well be the free tripeptide rather than the copper adduct
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