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ErbB2-targeted therapy response is enhanced by Cpt1a deletion in an immunocompetent ErbB2+ breast cancer GEMM Using RNA expression data from both microarray and mRNA sequencing, we confirmed that overexpression of CPT1A is a marker of poor prognosis correlating with decreased overall survival in all breast cancer patients ( p = 0.0035) and specifically in HER2+ breast tumors ( p = 0.00071) (Fig
The delayed gastric emptying contributes to enhanced feelings of fullness after eating, helping patients feel satisfied with smaller portion sizes
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