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This type of discomfort is typically related to the oesophagus or upper digestive tract rather than the heart itself

If additional review is needed: Intake may be paused for follow-up questions, which delays progression even if enrollment has already started

These effects are usually temporary, but it may help to listen to your body, avoid heavy meals, and take it easy if you feel slightly uncomfortable

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Considerations for Patients Starting or Switching to Insulin Glargine In insulin-nave patients, insulin glargine should be initiated at a starting dose of 0.2 U/kg or up to 10 U once daily