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This justifies the proposal of a theory integrating early concepts that offered partial explanations of the mechanism of aging with more recent ones like those shown in Table I(26-28), which allow us to state that aging results from the differentiation process shown by somatic cells, especially those unable to divide such as the neurons, in contrast with germ cells

The expression of DMT1 is significantly increased in the substantia nigra of PD patients, resulting in enhanced cellular uptake of Fe 2+

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