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Distribution Plasma Protein Binding 99% bound to plasma albumin
Weight loss goals should be personalized to each patient and weighed against risks of contributing to sarcopenia
doi:10.1073/pnas.1307701110
However, when symptoms occur, often due to the underlying condition rather than the elevated B12 itself, they may include 12 : Acne Headaches Anxiety Irregular heartbeats Trouble falling or staying asleep Nausea Fatigue Dizziness The symptoms of high vitamin B 12 are vague
Maintenance schedule Month 1-2 : Stay at current dose, assess stability Month 3-4 : Reduce by 2.5mg, monitor weight Month 5-6 : Reduce again if weight stable Long-term : Minimum dose that prevents regain Coming off tirzepatide Not recommended : Abruptly stopping often leads to rapid weight regain
