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Researchers have studied it for potential roles in: tendon healing ligament repair nerve regeneration inflammation control blood vessel growth Most of this research has been performed in animal models , where BPC-157 has shown interesting effects related to tissue repair
290,291,292 In macrophages, PKA regulates gene expression by phosphorylating transcription factors like CREB
Macrophages exhibit a heterogeneous and plastic phenotype, capable of polarizing into the pro-inflammatory M1 or the reparative and anti-inflammatory M2 phenotypes
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