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The most effective time for most people is in the morning on an empty stomach, about 30 minutes before breakfast

J., Leighton, B

A recent paper published in The Lancet showed that nearly 20% of participants in lifestyle interventions without medications gain weight, around 40% lose between 1-10% of their body weight, and just 13% lose more than 10%

Also, these are effective when the oral supplements you are consuming are not producing any results

When prescribed, it is typically given as a small subcutaneous injection, often timed in the evening to align with the body's natural nighttime growth-hormone release