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GLP-1R agonist 2 (100 nM, 1,000 nM) promotes glucose-dependent insulin secretion in CD1 mouse islets, and this effect is dependent on the GLP-1 receptor
The researchers found this promising in terms of mitigating some of the cardiometabolic issues that antipsychotic drugs may create
This will ensure a longer effect and less irritation
The results of the Evaluation of LIXisenatide in Acute coronary syndrome (ELIXA) trial, the first cardiovascular outcomes trial for the short-acting GLP-1 RA lixisenatide, were also published recently [52]
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