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In general, three phases of metabolic detoxification of xenobiotics have been often described in the literature

Hypoglycemia: When combined with insulin or insulin secretagogues, there is an increased risk of hypoglycemia, necessitating careful monitoring

GLP-1 receptor agonists as a class are tracked under the 2026 WADA Monitoring Program, which records patterns of use across sports without imposing sanctions

Higher fasting levels of GLP-1 have been reported in a different group of patients with vascular pathology such as aortic valve abnormality [42] suggesting that GLP-1 could be a broader marker for cardiovascular pathology