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Working concentration: Aliquot volumes are determined by each laboratory's own validated protocol
We therefore sought a strategy to reduce the scale of the library to remain within the quantitative throughput limits of our assay (up to ~40,000 substrates), while still assaying a full repertoire of sequences likely to be cleaved by our evolved proteases (Extended Data Fig
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It is a naturally occurring peptide whose physiological role is still being characterized, which makes it a subject of ongoing mechanism research rather than a compound with a single defined receptor
In practical research terms, BPC-157 is best understood as a synthetic research peptide used to investigate cytoprotection-associated endpoints, cell migration, angiogenesis-associated signaling, endothelial behavior, fibroblast biology, and tissue-repair-associated pathways in controlled laboratory models
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