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sALS and fALS share several features, including protein aggregation, motor neuron hyperexcitability, trafficking defects, disruption of nucleocytoplasmic transport, oxidative stress, mitochondrial dysfunction, glutamate excitotoxicity, and neuroinflammation

Jelsing J, Vrang N, Hansen G, Raun K, Tang-Christensen M, Bjerre Knudsen L

Which raises an interesting question: is the problem always the amount of fuel available - or could it be how efficiently that fuel is being used

Therefore, patients may need to consider other factors such as side effects, effectiveness and individual health circumstances when deciding between these two medications

This is essential for: Our ability to hold and maintain focus