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Manufacturers cannot claim glutathione 'treats liver disease,' 'cures oxidative stress disorders,' or 'prevents cancer'those are drug claims that trigger FDA enforcement
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This review does not comprehensively address APAP toxicity in specific vulnerable populations, such as neonates, pediatric patients, pregnant women, or the elderly, who may exhibit distinct pharmacokinetics, pharmacodynamics, and susceptibility to liver injury
The liver, which houses the highest glutathione concentrations and performs extensive detoxification work, increases its activity during sleep when digestive demands are minimal and energy can be directed toward cellular maintenance
doi: 10.1530/JOE-19-0486 66 de KloetER
