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113 It was then fused to the constant region (Fc) of modified human immunoglobulin G4 (IgG4) via a -(Gly-Gly-Gly-Gly-Ser) 3-Ala- bridge and exhibits an average biological half-life of 90 h
A., Aprikian, O., von Eynatten, M., & Johansen, O
The vast majority of IGF-1 is secreted by the liver (Laron, 2001) with tissues like skeletal muscle also contributing to IGF-1 release during resistance exercise (Perrone et al., 1995)
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