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According to clinical research parenteral administration (intramuscular or intravenous) is preferred over other drug administration routes in case of emergency situations as it provides first-pass metabolism avoidance, reliable therapeutic concentrations and better bioavailability of dosage (2) It can also be used in situations when oral route is not feasible
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For AOD-9604 specifically, the disulfide bond is also susceptible to oxidation at warmer temperatures if any oxygen is present
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