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The most frequently reported side effects in Phase 2 trials are gastrointestinal: nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation

5 Conclusions The absence of any effects of hepatic impairment on the PK of tirzepatide would suggest that a dose adjustment of tirzepatide, based on PK parameters, may not be required in people with hepatic impairment

Sources reviewed include: the official FeelGood website at feelgoodmeds.com, the brand's published Cancellation and Refund Policy, Terms of Use (last updated July 2025), the OpenLoop Healthcare Partners, PC telehealth consent form published at openloophealth.com, LegitScript verification data, and category-level published research on GLP-1 receptor agonists from NIDDK, NIH, and peer-reviewed clinical literature

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Despite its efficacy, some may be drawn to natural alternatives that align with a holistic approach to health